Well, that is immediate confirmation. Istredd reminds himself to never accidentally touch that part of that arm, it probably is a sensitive spot to him, considering.

It's possible. We're not in the same world, the same rules don't apply. There is a chance. Istredd obviously can't be the one to help them find what the loophole could be. His eyebrows shoot up at that last part and he frowns. This started because Istredd said he would protect Lucifer from Dean. He hasn't forgotten that or changed his mind. As long as you physically stay away from him.